Polynucleotides Consultation

What are polynucleotides? 

A polynucleotide consultation is an appointment with a qualified healthcare professional to discuss whether laboratory prepared polynucleotide products may be suitable for your skin concerns.

Polynucleotides are highly purified strands of DNA that are prepared in controlled laboratory conditions for cosmetic use. In Australia, these products are supplied as medical devices.

These products are not designed to change facial shape or add volume. They are often discussed in the context of supporting overall skin quality. Your practitioner will explain what is currently known about these products during your consultation.

What areas does a polynucleotide consultation address? 

Polynucleotides are often discussed for use in areas where people notice early changes in skin quality, including: 

• Under-eye area 

• Full face 

• Neck 

• Décolletage 

• Hands 

People usually enquire about these areas if they have noticed dullness, dryness or changes in texture. Your practitioner will assess whether any of these areas are appropriate for this type of procedure.

Who may be suitable for a polynucleotide consultation

People often enquire about a polynucleotides consultation when they have noticed changes such as:

• Fine lines or crepey looking skin

• Skin that feels dull or dehydrated

• Early signs of ageing in areas like the face, neck or hands 

Suitability is always assessed in a consultation with a qualified practitioner, based on your skin and health history. 

What happens during the polynucleotide consultation or procedure

During your consultation, your practitioner may:

• Review your skin and medical history
• Assess the areas you wish to focus on
• Explain how polynucleotide products are prepared
• Discuss treatment steps, scheduling and aftercare
• Outline risks and considerations

If you choose to proceed on another day, polynucleotides are placed beneath the skin in small amounts using a fine needle or cannula. Topical anaesthetic may be used to support comfort.

These products are applied with the aim of supporting overall skin quality. Your practitioner can provide further explanation during your consultation, as individual suitability varies.

Is there any downtime or aftercare? 

Downtime varies from person to person. You may experience:

• Redness or small bumps at injection sites
• Swelling or tenderness
• Bruising in some areas

Your practitioner will give personalised aftercare instructions, including when to avoid exercise, heat, makeup or active skincare.

Surgical or non-surgical? 

This is a non surgical injectable procedure. There are no incisions or stitches. Polynucleotides are often grouped within a category of products that are intended to support skin quality. They are classified as a medical device and not a scheduled medicine in Australia.

Who can perform polynucleotide procedures

Polynucleotides should only be administered by trained healthcare professionals with experience in facial anatomy. This includes doctors and nurses with appropriate qualifications. Your practitioner will work within their scope of practice and relevant Australian regulations.

All practitioners listed on Mirror Mirror have been independently verified to meet professional and safety standards. 

Consultation required? 

Yes. A consultation is always required before treatment to ensure: 

• The product is suitable for your skin and health history 

• Your expectations are realistic 

• You understand the treatment schedule, risks, and likely outcomes 

This supports your safety and ensures a personalised plan is in place. 

Risks and considerations 

Polynucleotides have known risks and side effects. These may include: 

• Redness, swelling, or bruising 

• Tenderness or small lumps at treatment sites 

• Allergic reaction

Results are gradual and depend on your body’s response. Your practitioner will guide you on what to expect and when to follow up. 

Frequently asked questions 

What are polynucleotides made from? 
Polynucleotide products are created from highly purified DNA, often sourced from fish. These materials are processed, sterilised and prepared under controlled conditions for cosmetic use as medical devices.

How do polynucleotides work?
These products are discussed in the context of supporting overall skin quality. Your practitioner will explain the current evidence and how these products are thought to interact with the skin during your consultation.

How many treatments will I need? 
Many people complete a series of sessions spaced a few weeks apart. The number of sessions varies based on your skin and your practitioner’s recommendation.

When will I see results? 
Responses vary. Some people feel their skin looks different in the weeks after their sessions as the skin settles. Your practitioner will discuss realistic timing for your situation.

Are polynucleotides the same as filler?
No. Polynucleotides are not designed to add volume or change the shape of the face. They are used with the aim of supporting overall skin quality rather than structure.

Can polynucleotides be combined with other procedures?
Sometimes yes, depending on your skin and timing. Your practitioner will advise which combinations may be suitable for you.